Table 3.

Multivariate analysis for breast cancer-specific mortality starting from year 5 after diagnosis stratified by hormone receptor status

Variable	Fine and Gray Model for HR +			Fine and Gray Model for HR−
	P	Hazard ratio	95.0%CI for hazard ratio	P	Hazard ratio	95.0%CI for hazard ratio
T
T1a		Reference			Reference
T1b	0.013	1.204	1.040–1.392	0.759	1.045	0.789–1.385
T1c	< 0.001	1.932	1.683–2.218	0.007	1.424	1.100–1.842
T2	< 0.001	3.052	2.655–3.508	< 0.001	1.826	1.410–2.363
N
N0		Reference			Reference
N1	< 0.001	1.949	1.869–2.032	< 0.001	1.721	1.562–1.896
N2	< 0.001	3.390	3.210–3.580	< 0.001	2.742	2.411–3.117
Age at diagnosis
< 50 years		Reference			Reference
50–64 years	0.007	0.940	0.899–0.983	0.006	1.152	1.042–1.273
> 64 years	0.002	1.077	1.027–1.130	< 0.001	1.397	1.244–1.568
Race
White		Reference			Reference
Black	< 0.001	1.290	1.206–1.379	0.072	1.123	0.990–1.273
Other	0.229	0.960	0.897–1.026	0.181	0.896	0.762–1.053
Grade
Grade I		Reference			Reference
Grade II	< 0.001	1.718	1.679–1.828	0.004	1.453	1.124–1.879
Grade III/IV	< 0.001	2.125	1.991–2.268	0.495	0.915	0.710–1.180
Marital status
Single		Reference			Reference
Married	< 0.001	0.887	0.838–0.939	0.383	0.941	0.821–1.079
Other	0.738	0.989	0.928–1.054	0.786	1.021	0.878–1.188
Year of diagnosis
Each additional year	< 0.001	0.944	0.940–0.948	< 0.001	0.946	0.936–0.955

CI confidence interval, HR + hormone receptor positive, HR− hormone receptor negative