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. 2021 Jul 23;11:15062. doi: 10.1038/s41598-021-94343-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Example plots taken from the Lafora disease study report. (A) Functional enrichment plot for GO Biological Processes overrepresented among genes in co-expression module 23. (B) Eigen-gene values for module 1, which represent averaged expression values for the genes within the module, as described in “Materials and methods” section, alongside external measure values for all significantly correlated categorical and continuous vectors significantly correlated with the eigen-values (p-value < 0.05), calculated as described in “Materials and methods” section.