Fig. 3. Reconstruction of the proto-cyclostome chromosomes and evidence of sixfold duplication of the genome.
a Japanese lamprey scaffolds are illustrated with the scaffold IDs. These scaffolds were partitioned into segments of conserved synteny, and segments corresponding to proto-vertebrate chromosome Pvc3 (blue) and Pvc17 (green) are shown for illustrative purposes. b Groups of segments of the same colour were organized into several subgroups representing proto-cyclostome chromosomes based on the distribution of paralogues and orthologues. c The triangular plot is a 45°-rotated graph of the paralogue distribution between the 12 proto-cyclostome chromosomes that correspond to Pvc3 and Pvc17. This shows large numbers of paralogues between the chromosomes (dots in the red regions) but few paralogues within each chromosome (dots in the yellow regions). d The table classifies the proto-vertebrate chromosomes with respect to the number of duplicated proto-cyclostome chromosomes as shown in the ‘Multiplicity' column (Pvc18 was retained as a single proto-cyclostome chromosome because Pvc18 had too many segments for the reconstruction algorithm). The table also shows the numbers and ratios of Japanese lamprey genes that were mapped to the proto-cyclostome chromosomes originating from the proto-vertebrate chromosomes shown in the ‘Chromosomes' column.