Table 2.
Exonic splicing enhancer motifs masked by the antisense oligonucleotides examined in this study.
| Gene | AO nomenclature | SRSF1 (SF2) | SRSF2 (SC35) | SRSF5 (SRp40) | SRSF6 (SRp55) |
|---|---|---|---|---|---|
| USH2A | H13A(−05+20) | 1 | 1 | 1 | 0 |
| H13A(+70+94) | 1 | 4 | 0 | 0 | |
| H13A(+136+160) | 1 | 1 | 2 | 0 | |
| H13A(+161+183) | 2 | 2 | 1 | 1 | |
| COL7A1 | H15A(+91+115) | 3 | 2 | 1 | 1 |
| H15D(+14–11) | 2 | 2 | 0 | 1 | |
| ATXN3 | H9A(+38+62) | 3 | 0 | 2 | 1 |
| H9D(+20–05) | 1 | 0 | 2 | 0 | |
| SRSF2 | H2A(+268+292) | 4 | 2 | 1 | 0 |
| H2D(+10–12) | 0 | 1 | 1 | 0 | |
| HTT | H12A(+269+297)a | 3 | 4 | 3 | 0 |
| LMNA | H11A(+221+245)a | 3 | 3 | 1 | 1 |
aNot tested in this study; published results.