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. 2021 Jul 23;4:906. doi: 10.1038/s42003-021-02381-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Heterogeneity of total CD45⁺ TILs from lung tumors all together (A) and separately under five different treatment conditions (Control, Adjuvant, CA170, KVAX vaccine and the combination of CA170 peptide plus KVAX vaccine) (B) in lung cancer shown by UMAP. C Feature plot shows representative genes for the different types of immune cells: CD4⁺, CD8⁺, B cells (Cd19), NK cells (Ncr1), Tregs (Foxp3), and Myeloid cell-specific genes (Cd3e, Itgam, Itgax, Csf1r) across all clusters for the five treatment conditions. D The bar plot shows the percentage of different immune cells under five different treatment conditions individually.