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. 2021 Jul 23;11:15106. doi: 10.1038/s41598-021-94676-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Left: enhanced depth imaging-optical coherence tomography (EDI-OCT) scan of macular region with marked retinal pigment epithelium (blue line) and scleral-uveal junction (red line). Middle: fundus photography with the Early Treatment Diabetic Retinopathy Study (ETDRS) grid applied. Averaged measurements from the central ETDRS region are presented as the averaged thickness center (ATC) and to the average volume center (AVC). Averaged volumetric measurements from the entire area of the ETDRS grid are presented as average volume (AV). Right: the averaged measurements of choroidal thickness (μm) (marked in black) and volume (mm³) (marked in red) presented for 9 ETDRS subfields. Values of AV displayed in green.