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. 2021 Mar 21;35(8):2086–2109. doi: 10.1038/s41433-021-01501-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 17 — A Peripheral break present, ICM breaks absent and no dehiscence at Locus minoris resistantiae: only peripheral break contributes to the RD and RD does not extend into coloboma. B Peripheral break present, dehiscence at Locus minoris resistantiae present, ICM break absent: only peripheral break contributes to RD but RD extends into the coloboma. C ICM break present, dehiscence at Locus Minoris resistantiae present, peripheral retinal break absent: fluid spreads through ICM break to cause ICM detachment before spreading beyond coloboma to cause RD. D ICM break present, dehiscence at Locus minoris resistantiae present, peripheral retinal break present: fluid enters sub-retinal space both from peripheral retinal break and through break in ICM.