Table 2.
Basic Features of the Included Studies
| Included Studies | Diagnostic Criteria | Sample Size (T/C) | Sex (Men/Women) | Age (Year) | Course of Disease (Year) |
|---|---|---|---|---|---|
| Zhang 201111 | ACR | 30/30 | 22/38 | 58.2 | – |
| Zhou 201412 | ACR | 39/44/22 | T:14/25 C1:8/36 C2:5/17 |
T:67±10 C1:80±10 C2:66±12 |
T:3 C1:2.02 C2:1.53 |
| Zhou 201713 | ACR | 30/30 | T:14/16 C:13/17 |
T:59.07±7.89 C:60.60±8.27 |
T:5.73±2.85 C:5.50±2.54 |
| Ren 201114 | ACR | 31/28 | T:11/20 C:8/20 |
T:64.03±7.24 C:62.57±8.12 |
T:6.82±6.60 C:7.15±7.72 |
| Zhou 201515 | ACR | 40/40 | T:17/23 C:19/21 |
T:54.6±5.3 C:53.8±7.6 |
T:17.2±2.2 (month) C:15.6±3.0 (month) |
| Zhang 201816 | ACR | 39/39 | T:13/26 C:15/24 |
T:61.36±2.24 C:62.08±2.46 |
T:4.77±0.12 C:4.68±0.28 |
| Liu 202017 | Guidelines for the diagnosis and treatment of osteoarthritis | 41/37 | T:2/39 C:3/34 |
T:61.72±8.05 C:60.98±7.56 |
T:2.13±0.98 C:2.53±0.83 |
| Guo 201618 | Guidelines for the diagnosis and treatment of osteoarthritis | 45/45 | T:19/26 C:17/28 |
T:56.00±7.25 C:57.17±6.96 |
T:33.75±14.11 (month) C:32.35±13.72 (month) |
| Wu 201519 | ACR | 47/48 | – | T:58.75±1.21 C:60.02±2.17 |
T:18±2 (month) C:19±3 (month) |
| Qiu 200620 | ACR | 30/30 | T:5/25 C:4/26 |
T:56.07 C:55.37 |
T:8.95 C:9.55 |
| Gang2 01621 | Guidelines for the diagnosis and treatment of osteoarthritis | 43/45 | T:19/24 C:22/23 |
T:54±8 C:54±8 |
T:1.1±0.6 C:1.2±0.6 |
| Gao 201122 | ACR | 34/35 | T:13/21 C:15/20 |
T:57.68±8.67 C:58.57±8.89 |
T:37.35±10.83 (month) C:38.86±12.12 (month) |
| Wang 201723 | Diagnostic criteria for blood stasis type of KOA | 48/47 | T:25/23 C:24/23 |
T:56.15±7.36 C:56.19±7.33 |
– |
| Yin 201724 | Guidelines for the diagnosis and treatment of osteoarthritis | 60/60 | – | – | – |
| Ju 201725 | ACR | 30/30 | T:6/24 C:7/23 |
T:60±10 C:64±6 |
T:29.89±29.74 (month) C:32.74±31.43 (month) |
| Wu 201226 | ACR | 30/30 | T:11/19 C:13/17 |
T:60.63±6.44 C:59.87±6.77 |
T:3.47±1.27 C:3.23±1.48 |
| Chen 201827 | Guidelines for the diagnosis and treatment of osteoarthritis | 45/45 | T:31/14 C:28/17 |
T:65.51±3.26 C:66.36±3.08 |
T:3.56±1.87 C:3.49±1.76 |
| Liu 201428 | ACR | 30/30 | T:10/20 C:12/18 |
T:58.07±8.76 C:59.47±7.92 |
– |
| Tan 201629 | Guidelines for the diagnosis and treatment of osteoarthritis | 40/40 | T:18/22 C:17/23 |
T:52.72±5.83 C:51.93±6.18 |
T:1–10 C:1–12 |
| Ma 201530 | Guidelines for the diagnosis and treatment of osteoarthritis | 54/54 | T:22/32 C:19/35 |
T:53.2±7.5 C:56.3±8.6 |
T:3.2±1.4 C:4.4±1.5 |
| Chen 201231 | ACR | 30/30 | T:8/22 C:9/21 |
T:59±12 C:59±16 |
T:50.23±47.50 (month) C:62.20±45.67 (month) |
| Jiang 201332 | ACR | 42/44 | T:18/24 C:21/23 |
T:65.7±3.9 C:67.7±4.5 |
T:3.7±0.9 C:4.2±1.5 |
| Ren 201833 | ACR | 54/54 | T:23/31 C:25/29 |
T:67.1±4.6 C:68.7±5.2 |
T:4.9±1.5 C:4.6±1.7 |
| Zhang 201634 | Standard of diagnosis and curative effect of disease and syndrome in TCM | 30/30 | T:18/12 C:19/11 |
T:56.0±2.9 C:55.9±2.8 |
T:5.6±0.5 C:5.7±0.5 |
| Pan 202035 | ACR | 35/35 | T:11/24 C:9/26 |
T:65.086 C:64.2 |
T:3.34±1.72 C:3.03±1.33 |
| Ji 201236 | Guiding principles of clinical research on new chinese medicine | 30/30 | T:12/18 C:11/19 |
T:56.73±10.08 C:58.77±7.98 |
T:38.17±23.99 (month) C:39.23±25.54 (month) |
| Shen 201737 | Standard of diagnosis and curative effect of disease and syndrome in TCM | 100/100 | T:54/46 C:51/49 |
T:66.12±2.09 C:66.51±2.12 |
T:3.31±0.23 C:3.35±0.12 |
| Miao 201438 | Guidelines for the diagnosis and treatment of osteoarthritis | 35/35/35 | T:5/30 C1:9/26 C2:7/28 |
T:57.5±9.7 C1:56.3±8.9 C2:60.4±10.5 |
T:5.6±3.8 C1:6.4±4.2 C2:6.8±3.3 |
| Zhang 201639 | Guidelines for the diagnosis and treatment of arthritis | 28/28 | T:11/17 C:12/16 |
T:62.3±5.1 C:61.8±4.7 |
T:8.7±3.6 C:8.4±3.4 |
| Lin 201840 | The National Institute for Health and Clinical Excellence Guidelines 2014 Edition criteria | 21/21 | T:4/17 C:1/20 |
T:59.5±7.5 C:60.0±7.3 |
T:60.0±45.9(month) C:63.1±45.4(month) |
| Zhao 201441 | ACR | 55/55 | T:16/39 C:21/34 |
T:65.80±7.45 C:64.55±8.38 |
– |
| Zhang 201342 | ACR | 33/34 | T:13/20 C:14/20 |
T:57±8 C:58±9 |
T:38±10 (month) C:38±11 (month) |
| Zheng 201643 | ACR | 35/35 | T:16/19 C:15/20 |
T:62.39±8.004 C:61.41±8.203 |
T:135.97±74.068 (month) C:128.03±70.194 (month) |
| Lu 201144 | ACR | 27/27 | T:6/21 C:8/19 |
T:54.11±9.46 C:60.81±10.09 |
T:3.83±5.78 C:3.69±2.98 |
| Li 202045 | Guidelines for the diagnosis and treatment of osteoarthritis | 36/36 | T:12/24 C:14/22 |
T:58.54±8.41 C:56.52±7.91 |
– |
| Tang 201746 | Guidelines for the diagnosis and treatment of osteoarthritis | 30/30 | T:8/22 C:9/21 |
T:59.64 C:60.40 |
T:2.62 C:2.73 |
| Song 202047 | Guidelines for the diagnosis and treatment of osteoarthritis | 30/30 | T:12/18 C:14/16 |
T:53.83±5.37 C:53.47±7.34 |
T:37.90±16.01 (month) C:34.67±19.78 (month) |
| Lin 201248 | Guidelines for the diagnosis and treatment of osteoarthritis | 30/30 | T:14/16 C:16/14 |
T:48.47±11.95 C:50.07±9.7 |
T:4.97±7.1 (month) C:9.83±17.74 (month) |
| He 201849 | ACR | 57/55 | T:26/31 C:22/33 |
T:56±5 C:58±5 |
T:73.28±29.24 (month) C:71.09±27.96 (month) |
| Fan 201650 | Guidelines for the diagnosis and treatment of osteoarthritis | 54/54 | T:33/21 C:30/24 |
T:58±6.2 C:56±8.4 |
T:14.8±8.8 (month) C:12.7± 7.3 (month) |
Abbreviations: ACR, American College of Rheumatology; T, treatment group; C, control group; -, not mentioned.