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. 2021 Jul 19;14:2209–2228. doi: 10.2147/JPR.S315956

Table 3.

Characteristics of Interventions

Included Studies Study Type Interventions Course of Treatment (Week) Outcome Indicators
Treatment Group Control Group
Zhang 201111 Double-arm Moxibustion celecoxib 200 mg, 1/d 6 d,e
Zhou 201412 Three-arm Moxibustion C1:electro-acupuncture
C2:celecoxib 200 mg, 1/d
4 d
Zhou 201713 Double-arm Moxibustion Diclofenac sodium gel 4 a,b,c,d
Ren 201114 Double-arm Moxibustion Sham moxibustion 6 a,b,c
Zhou 201515 Double-arm Electro-acupuncture Diclofenac sodium sustained release capsules 50 mg, 1/d 4 d
Zhang 201816 Double-arm Electro-acupuncture Meloxicam dispersible tablets 7.5 mg, 1/d 2 d
Liu 202017 Double-arm Electro-acupuncture Conventional acupuncture 4 d
Guo 201618 Double-arm Electro-acupuncture Diclofenac sodium double release enteric capsules 75 mg, 1/d 3 a,b,c
Wu 201519 Double-arm Electro-acupuncture Votalin emulsion 4 d
Qiu 200620 Double-arm Electro-acupuncture Futarin sustained-release tablets 75 mg, 1/d 4 a,b,c,e
Gang 201621 Double-arm Electro-acupuncture Meloxicam tablets 7.5 mg, 1/d 6 a,b,c
Gao 201122 Double-arm Electro-acupuncture Warm needle 8 a,b,c,d
Wang 201723 Double-arm Electro-acupuncture Warm needle 3 d
Yin 201724 Double-arm Electro-acupuncture Glucosamine 240 mg, 1/d 8 a,b,e
Ju 201725 Double-arm Electro-acupuncture Celecoxib capsules 200 mg, 1/d 2 a,b,c,d
Wu 201226 Double-arm Electro-acupuncture Conventional acupuncture 4 a,b,c
Chen 201827 Double-arm Warm needle Glucosamine sulfate capsules 314 mg, 2 capsules/times, 3 times/ d 4 a,b,c
Liu 201428 Double-arm Warm needle Electro-acupuncture 4 a,b,c
Tan 201629 Double-arm Warm needle Conventional acupuncture 3 d
Ma 201530 Double-arm Warm needle Conventional acupuncture 4 d
Chen 201231 Double-arm Warm needle Ibuprofen sustained release capsules 300 mg, 2 times/d 3 a,b,c,e
Jiang 201332 Double-arm Warm needle Glucosamine sulfate tablets 314 mg, 2 tablets/times, 3 times/d 8 a,b.c.e
Ren 201833 Double-arm Warm needle Glucosamine hydrochloride tablets 240 mg, 2 tablets/times, 3 times/d 20 a,b,c
Zhang 201634 Double-arm Warm needle Conventional acupuncture 4 a,b,c,d
Pan 202035 Double-arm Acupoint catgut embedding Conventional acupuncture 3 d
Ji 201236 Double-arm Electro-acupuncture Warm needle 8 a,b,c,d
Shen 201737 Double-arm Conventional acupuncture Diclofenac sodium emulsion 4 b,c,e
Miao 201438 Three-arm Moxibustion C1: electro-acupuncture
C2: celecoxib capsules 200 mg, 1/d
4 d
Zhang 201639 Double-arm Conventional acupuncture Warm needle 4 e
Lin 201840 Double-arm Conventional acupuncture Sham acupuncture 26 a,b,d,e
Zhao 201441 Double-arm Moxibustion Sham moxibustion 6 a,c,e
Zhang 201342 Double-arm Fire needle Warm needle 4 a,b,c,d
Guo 201643 Double-arm Fire needle Conventional acupuncture 3 a,b,d
Lu 201144 Double-arm Fire needle Warm needle 4 d,e
Li 202045 Double-arm Fire needle Conventional acupuncture 24 d
Tang 201746 Double-arm Fire needle Warm needle 4 a,b,c,d
Song 202047 Double-arm Fire needle Celecoxib capsules 200 mg, 1/d; diclofenac sodium diethylamine emulsion agent 200 mg, 3 times/d 3 d
Lin 201248 Double-arm Fire needle Conventional acupuncture 4 d,e
He 201849 Double-arm Electro-acupuncture Fire needle 4 a,b,c,d,e
Fan 201650 Double-arm Fire needle Warm needle 4 a

Notes: a, WOMAC pain scores; b, WOMAC stiffness scores; c, WOMAC joint function scores; d, VAS scores; e. Adverse events.