Table 5.
Mean haematological parameters before and after transfusion of 2 units of FFP
| Parameters | Pre Transfusion Mean (M1) | Post Transfusion Mean (M2) | Mean Difference (M2-M1) | 0.95 CI of difference | Paired t-test | p-value |
|---|---|---|---|---|---|---|
| Haemoglobin (g/dL) | 6.72+1.59 | 6.56+1.60 | -0.16+0.26 | (-0.01)-(-0.31) | 2.27 | <0.05 |
| RBC count (millions/mm3) | 2.85+0.57 | 2.79+0.57 | -0.06+0.11 | (-0.12)-0.01 | 1.96 | >0.05 |
| Haematocrit (%) | 21.36+4.61 | 20.92+4.68 | -0.44+0.81 | (-0.91)-0.03 | 2.05 | >0.05 |
| Total leukocyte count (/mm3) | 14,279+3250 | 13,857+3041 | -422+948 | (-968)-126 | 1.66 | >0.05 |
| Platelet count (lakhs/mm3) | 1.46+0.49 | 1.44+0.47 | -0.02+0.04 | (-0.05)-0.003 | 1.88 | >0.05 |
| MCV (fL) | 75.04+6.15 | 75.03+6.13 | -0.01+0.03 | (-0.02)-0.01 | 1.000 | >0.05 |
| MCH (pg) | 23.28+2.64 | 23.28+2.64 | 0.00 | - | - | - |
| MCHC (g/dL) | 31.41+3.40 | 31.32+3.33 | -0.09+0.24 | (-0.23)-0.05 | -1.33 | >0.05 |
| RDW (%) | 15.33+1.47 | 15.29+1.53 | -0.04+0.23 | (-0.18)-0.09 | 0.68 | >0.05 |
| Bleeding time* (sec) | 234.64+65.27 | 222.86+56.18 | -11.78+16.94 | (-2.01)-(-21.57) | -2.60 | <0.05* |
| Clotting time* (sec) | 592.14+84.21 | 395.71+93.70 | -196.4+56.69 | (-127.08)-(-265.77) | -5.83 | <0.05* |
| Prothrombin time (sec)* | 19.29+1.33 | 16.64+0.93 | -2.64+0.63 | (-2.28)-(-3.01) | -15.61 | <0.05* |
| Clot retraction (%)* | 53.50+7.52 | 50.86+3.37 | -2.64+7.90 | (-7.20)-1.92 | -1.25 | >0.05 |
*
Indicates clinically insignificant increment.