Table 3.

Baraclude and tenofovir for treatment of HBV-associated liver disease in CKD. * compensated liver disease.

Creatinine Clearance	Entecavir *	Tenofovir Disoproxil *
>50 mL/min/1.73 m2	0.5 mg per day	245 mg per day
30–49 mL/min/1.73 m2	0.25 mg per day	245 mg/48 h
10–29 mL/min/1.73 m2	0.15 mg per day	245 mg x2/week
<10 mL/min/1.73 m2 (including patients on dialysis)	0.05 mg per day	245 mg/week