Table 1.
Selected biochemical parameters in all children with INS and in examined subgroups according to the number of relapses and treatment modality. Data are presented as median values and interquartile ranges.
| Parameter Group | Serum Albumin [g/dL] |
Total Cholesterol [mg/dL] |
Protein/Creatinine Ratio [g Protein/g Creatinine] |
CRP [mg/L] |
|---|---|---|---|---|
| Total INS N = 51 |
1.90 (1.05–2.55) |
363.0 (268.0–475.0) |
6.2 (3.0–10.6) |
2.90 (0.80–3.60) |
| Group IA N = 20 |
1.70 (1.40–2.20) |
372.0 (297.0–464.0) |
4.85 (2.40–7.90) |
1.75 (0.40–3.60) |
| Group IB N = 31 |
2.40 (1.00–3.10) |
329.5 (238.0–601.0) |
7.0 (3.9–10.7) |
3.10 (1.65–3.69) |
| Group IIA N = 26 |
1.90 (1.10–2.50) |
366.5 (286.5–442.5) |
4.71 (2.5–7.76) a |
3.30 (1.40–3.60) |
| Group IIB N = 22 |
2.0 (1.00–2.50) |
329.5 (264.0–636.0) |
9.6 (6.2–19.2) |
2.56 (1.60–4.20) |
a—group IIA versus group IIB, p = 0.023, Kruskal-Wallis test. INS, idiopathic nephrotic syndrome; CRP, C-reactive protein; Group IA- children with the first occurrence of INS; Group IB- children with relapses of INS; Group IIA- children treated only with GCS, gluco-corticosteroids; Group IIB- children treated with GCS and corticosteroid-sparing agents.