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. 2021 Jun 23;11(7):1140. doi: 10.3390/diagnostics11071140

Table 1.

The function of IL-13Rα2 and the control of the expression in pancreatic cancer.

Function of
IL-13Rα2		 Activate ERK 1/2, c-jun, and c-fos
Increase transcription of MMPs
Promote tumor invasion and metastasis
Associated to perineural invasion
Shorten patient’ survival time
Control of
Expression		 Histone acetylation enables IL-13Rα2 expression
c-jun increases transcription of IL-13Rα2