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Reduction in citrullinated protein in RA patients treated with tocilizumab. Sera from RA patients at baseline or at 6 months after tocilizumab (TCZ) treatment were separated by SDS-PAGE then stained with CBB or were subjected to Western blot analysis with anti-modified citrulline (AMC) antibodies. Bars show means ± SEMs. p values were calculated using the unpaired t-test; * p < 0.05.
