Table 1.
MIC of the synthesized compounds against sensitive and resistant microorganisms.
| Sample | Minimum Inhibitory Concentration (µg/mL) | |||||
|---|---|---|---|---|---|---|
| Gram Positive Bacteria | Gram Negative Bacteria | Fungus | ||||
| Sensitive Staphylococcus aureus ATCC 25923 | Methicillin-Resistant Staphylococcus aureus (MRSA) ATCC-BAA-1720 | Sensitive Pseudomonas aeruginosa ATCC10145 | Penicillins and Cephalosporins-Resistant Pseudomonas aeruginosa ATCC BAA-2108 | Azole-Sensitive Candida albicans ATCC 18804 | Azole-Resistant Candida albicans ATCC 10231 | |
| 5a | 1.91 | 3.82 | 18.23 | 1.55 | NA a | NA |
| 5b | 3.37 | 1.85 | 3.92 | 14.29 | 2.61 | NA |
| 5c | 7.81 | 5.74 | NA | NA | 62.5 | NA |
| 5d | 0.15 | 0.49 | NA | NA | 0.29 | 19.07 |
| 5e | 1.82 | 2.91 | 5.07 | 62.5 | 25.48 | NA |
| 5f | 31.25 | 15.13 | 3.04 | 1.79 | 22.93 | NA |
| 9a | 1.90 | 5.30 | 3.97 | 14.81 | 3.93 | 13.91 |
| 9b | 5.29 | 1.27 | 10.13 | NA | 11.53 | NA |
| 9c | 0.43 | 3.13 | NA | NA | NA | NA |
| 9d | 0.71 | 0.42 | 0.93 | 1.84 | 0.65 | 2.17 |
| 9e | 0.48 | 9.19 | 0.93 | 3.91 | 4.49 | 15.04 |
| 13 | 9.04 | 7.29 | NA | NA | 250 | NA |
| 14 | 0.49 | 1.13 | NA | 1.49 | 0.18 | 3.18 |
| Vancomycin | 0.24 | 0.98 | 0.49 | 3.9 | ND | ND |
| Amphotericin B b | ND | ND | ND | ND | 0.24 | 1.95 |
a NA, not active b ND, not determined.