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CSF levels of TNF and sTNFRs in MS patients stratified according to the high (MS-High) or low (MS-Low) cortical lesion load. Significant increased levels of TNF (*** p < 0.001), sTNFR1 (** p < 0.01) and sTNFR2 (** p < 0.01) were detected in CSF of MS-High compared to MS-Low patients at time of diagnosis.
