Table 2.
CSF inflammatory pattern associated with differential cortical lesion load.
| Molecule | MS-High | MS-Low | Fold Change | ||
|---|---|---|---|---|---|
| Mean | StDev | Mean | StDev | ||
| TNF-α *** | 57.72 | 25.37 | 23.21 | 20.74 | 2.49 |
| sTNF-R1 ** | 6367.02 | 545.69 | 3465.76 | 1698.50 | 1.84 |
| sTNF-R2 ** | 1601.67 | 357.31 | 866.46 | 652.85 | 1.85 |
| BAFF/ TNFSF13B ** | 10,926.91 | 760.80 | 9049.70 | 6004.98 | 1.21 |
| LIGHT/ TNFSF14 ** | 663.90 | 105.88 | 156.56 | 256.93 | 4.24 |
| IFN-γ ** | 24.77 | 9.33 | 9.85 | 14.12 | 2.51 |
| BCA-1/ CXCL13 *** | 27.77 | 3.81 | 3.17 | 4.87 | 8.75 |
| IL-10 ** | 22.19 | 3.22 | 18.04 | 17.12 | 1.23 |
| IL-22 * | 52.64 | 26.72 | 33.62 | 36.19 | 1.57 |
| IL-27(p28) * | 271.39 | 51.76 | 139.56 | 171.48 | 1.94 |
| Osteopontin/SPP1 ** | 108,631.45 | 10,203.80 | 70,400.60 | 81,511.52 | 1.54 |
| Pentraxin-3 * | 529.91 | 72.04 | 282.65 | 414.24 | 1.87 |
| sCD163 ** | 55,404.70 | 2111.60 | 44,373.96 | 35,703.43 | 1.24 |
| Chitinase 3-like 1 ** | 52,758.42 | 4285.75 | 37,362.73 | 30,994.71 | 1.41 |
| IgM * | 707.97 | 61.54 | 346.19 | 338.14 | 2.05 |
| Fibrinogen * | 1483.38 | 184.83 | 941.78 | 6.64 | 1.58 |
| NF-L * | 2.82 | 0.68 | 1.62 | 0.95 | 1.74 |
| IL-28A/IFN-λ2 * | 243.89 | 67.45 | 350.47 | 91.71 | 0.57 |
| IL-12(p70) * | 9.00 | 3.87 | 13.81 | 2.53 | 0.62 |
* p < 0.05; ** p < 0.01; *** p < 0.001.