Table 3.
Results of the cox regression analysis on the impact of the anti-infective strategies (I)–(III) on the time from leukocytes <1/nL to ≥1/nL and results of the multivariate linear regression analysis on the duration of inpatient stay.
| Variable | Time to Leukocytes ≥ 1/nL | Duration of Inpatient Stay | ||
|---|---|---|---|---|
| HR (95% CI) | p-Value | Estimate (95% CI) | p-Value | |
| G-CSF support (vs. antibiotic prophylaxis) | 16.22 (10.88–24.18) | <0.001 | −0.19 (−0.25–−0.12) | <0.001 |
| No prophylaxis (vs. antibiotic prophylaxis) | 1.10 (0.72–1.69) | 0.65 | 0.06 (−0.03–0.15) | 0.16 |
| Age (per ten years) | 1.00 (0.82–1.21) | 0.97 | 0.07 (0.04–0.11) | <0.001 |
| ASCT at relapse (vs. first-line treatment) | 0.86 (0.60–1.25) | 0.44 | 0.06 (−0.02–0.13) | 0.13 |
| ≥VGPR before ASCT (vs. ≤PR) | 1.15 (0.85–1.55) | 0.38 | 0.05 (−0.01–0.11) | 0.12 |
| Stem cell amount ≥ 2.5 * (vs. <2.5) | 1.36 (0.94–1.96) | 0.10 | −0.07 (−0.14–0.00) | 0.06 |
Abbreviations: ASCT, autologous stem cell transplantation; CI, confidence interval; HR, Hazard Ratio; S.E., standard error; VGPR, very good partial remission; * ≥2.5 × 106 CD34+ cells per kg of body weight.