Table 4.

Multivariable mixed effects model on the impact of the anti-infective strategy on the need of carbapenems.

Variable	Need of Carbapenems
	OR (95% CI)	p-Value
G-CSF support (vs. antibiotic prophylaxis)	0.76 (0.32–1.80)	0.54
No prophylaxis (vs. antibiotic prophylaxis)	5.64 (1.24–25.63)	0.03
Age (per ten years)	1.20 (0.72–2.02)	0.48
ASCT at relapse (vs. first-line treatment)	2.08 (0.73–5.96)	0.17
≥VGPR before ASCT (vs. ≤PR)	1.40 (0.61–3.21)	0.42
Stem cell amount ≥ 2.5 * (vs. <2.5)	0.42 (0.14–1.23)	0.11

Abbreviations: ASCT, autologous stem cell transplantation; CI, confidence interval; G-CSF, granulocyte-colony stimulating factor; OR, Odds Ratio; PR, partial response; VGPR, very good partial response; * ≥2.5 × 10⁶ CD34⁺ cells per kg of body weight.