Table A1.
Exogenous viruses with similarity to ERVK integrase based on BLASTp search.
| Host | Species | Protein Name | Accession Number | Database | Percent Identity | E Value | Alignment |
|---|---|---|---|---|---|---|---|
| Retroviridae—Betaretrovirus | |||||||
| Mus Musculus | Mouse mammary tumor virus (MMTV) |
MMTV strain BR6 Integrase, partial | 5CZ2_A | nr | 56.46% | 3.00 × 10−71 | |
| Unnamed protein product | CAA25954.1 | nr | 52.36% | 2.00 × 10−70 | |||
| Chain A. Integrase (Core model of the MMTV Intasome) |
3JCA_A | nr | 51.50% | 2.00 × 10−82 | |||
| Pr160 | NP_056880.1 | nr | 51.11% | 7.00 × 10−76 | |||
| Pr160 gag pro pol precursor | AAA46542.1 | nr | 51.11% | 7.00 × 10−76 | |||
| p30DU-p13PR-RT-IN | NP_955564.1 | nr | 51.11% | 2.00 × 10−76 | |||
| Gag-Pro-Pol polyprotein | P11283.2 | nr | 51.11% | 3.00 × 10−75 | |||
| MMTV putative integrase | AAC24859.1 | nr | 50.37% | 5.00 × 10−81 | |||
| Gag-Pol-Pro polyprotein, partial | BAA03767.1 | nr | 49.65% | 1.00 × 10−77 | |||
| Exogenous MMTV Gag-Pro-Pol | AAF31469.1 | nr | 49.65% | 4.00 × 10−76 | • | ||
| Endogenous MTV1 Gag-Pro-Pol | AAF31464.1 | nr | 49.65% | 4.00 × 10−76 | |||
| Capra hircus | Enzootic Nasal Tumor Virus (ENTV) |
Pol protein, partial | AVG72436.1 | nr | 48.79% | 3.00 × 10−72 | |
| Pol protein, partial | AVG72437.1 | nr | 48.79% | 3.00 × 10−71 | |||
| Pol protein, partial | AVG72438.1 | nr | 48.79% | 7.00 × 10−71 | |||
| Pol protein, partial | AVG72441.1 | nr | 48.39% | 3.00 × 10−71 | |||
| Pol protein, partial | AVG72440.1 | nr | 48.39% | 4.00 × 10−71 | |||
| Pol protein, partial | AVG72435.1 | nr | 48.39% | 2.00 × 10−70 | |||
| Gag-Pro-Pol protein | QBP05340.1 | nr | 47.41% | 3.00 × 10−73 | |||
| Pol protein, partial | ANG58667.1 | nr | 47.41% | 2.00 × 10−72 | |||
| Pol protein | QEQ26602.1 | nr | 47.41% | 3.00 × 10−72 | |||
| Pol protein, partial | ANG58699.1 | nr | 47.41% | 2.00 × 10−71 | • | ||
| Pol protein, partial | ANG58695.1 | nr | 47.41% | 2.00 × 10−71 | |||
| Pol protein, partial | ANG58691.1 | nr | 47.41% | 2.00 × 10−71 | |||
| Pol protein, partial | ANG58679.1 | nr | 47.41% | 5.00 × 10−71 | |||
| Endogenous ENTV pol protein | QPG92760.1 | nr | 47.41% | 3.00 × 10−73 | |||
| Endogenous ENTV pol protein | QPG92768.1 | nr | 47.41% | 1.00 × 10−72 | |||
| Gag-Pro-Pol, partial | AOZ60515.1 | nr | 47.04% | 1.00 × 10−72 | |||
| Pol protein, partial | ANG58671.1 | nr | 47.04% | 1.00 × 10−71 | |||
| Pol protein, partial | ANG58683.1 | nr | 47.04% | 3.00 × 10−70 | |||
| Pol protein, partial | ANG58687.1 | nr | 47.04% | 2.00 × 10−71 | |||
| Pol protein, partial | ANG58663.1 | nr | 47.04% | 8.00 × 10−71 | |||
| Gag-Pro-Pol protein | ANC55859.1 | nr | 46.67% | 5.00 × 10−73 | |||
| Gag-Pro-Pol protein, partial | ADI50273.1 | nr | 46.67% | 4.00 × 10−72 | |||
| Gag-Pro-Pol protein, partial | AOZ60519.1 | nr | 46.67% | 7.00 × 10−72 | |||
| Pol protein, partial | ANG58675.1 | nr | 46.67% | 3.00 × 10−71 | |||
| Gag-Pro-Pol fusion, partial | NP_862833.2 | nr | 46.67% | 7.00 × 10−71 | |||
| Pol protein, partial | ANG58659.1 | nr | 46.10% | 1.00 × 10−72 | |||
| Macaca genus | Mason-Pfizer monkey virus (M-PMV) |
Simian AIDS retrovirus SRV-1-Pol polyprotein | GNLJSA | nr | 48.30% | 2.00 × 10−70 | |
| Simian retrovirus SRV-5-Pol polyprotein | BBG56792.1 | nr | 47.57% | 5.00 × 10−71 | • | ||
| Simian retrovirus SRV-Y-Pol protein, partial | BAM71050.1 | nr | 47.57% | 2.00 × 10−70 | |||
| Ovis Aries | Jaagsiekte sheep retrovirus | Reverse transcriptase, partial | CAA77117.1 | nr | 46.67% | 5.00 × 10−75 | |
| Reverse transcriptase, partial | CAA77113.1 | nr | 46.67% | 2.00 × 10−74 | |||
| Pol protein | NP_041186.1 | nr | 46.30% | 1.00 × 10−70 | • | ||
BLAST databases: nr denotes non-redundant protein database. Circle symbol: denotes integrase sequences used in protein alignment in Figure 1.