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. 2021 Jul 5;10(7):1698. doi: 10.3390/cells10071698

Table 1.

Patient characteristics and their associations with Eg5 expression.

Variables N (%) Eg5
Mean ± SD p
Total 108 (100) 8.3 ± 16.0 #
Mean age (SD, years) 54.7 (13.4) #
Gender 0.887
Female 21 (19) 8.7 ± 10.6
Male 87 (81) 8.2 ± 17.1
Hepatitis virus
HBsAg positive 75 (69) 8.3 ± 15.6 0.964
Anti-HCV positive 31 (29) 6.9 ± 16.6 0.578
AJCC stage 0.573
I 46 (43) 7.5 ± 19.8
II 32 (30) 7.0 ± 8.5
III 30 (28) 10.9 ± 15.8
Tumor size 0.835
>5 cm 48 (44) 8.7 ± 19.3
≤5 cm 60 (56) 8.0 ± 12.9
Tumor grade 0.683
1 26 (24) 10.3 ± 24.4
2 51 (47) 7.0 ± 14.0
3 31 (29) 8.8 ± 9.1
AFP > 400 ng/mL 40 (37) 9.4 ± 14.8 0.573
Child-Pugh status 0.828
A 100 (93) 8.4 ± 16.4
B 8 (7) 7.1 ± 9.7

Abbreviations: SD = standard deviation; HBsAg = hepatitis B virus surface antigen; HCV = hepatitis C virus; AJCC = American Joint Committee on Cancer; AFP = α-fetoprotein. # Age had a weakly positive correlation with Eg5 expression (r = 0.013, p = 0.897). Calculated using the method described in Section 2.2. p values were conducted using the independent t test or one-way analysis of variance.