Figure 1.

ACE, and chemokine mRNA expression is increased in placenta of pregnancies complicated by preterm labor with chorioamnionitis (ChA). Bar charts show the relative levels of ACE2 (A), CCL2 (B), IL-6 (C), and IL-8 (D) mRNA in placentas from PTB, ChA, SVD and ELCS deliveries, assessed by real time qPCR. Data are normalized by the geometric mean of TOP1 and YWHAZ (reference genes), n = 6/7/group. Statistical differences were tested by Tukey’s multiple comparisons test. Data are presented as mean ± SEM. Different letters indicate a difference between groups of p < 0.05.