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. 2021 Jul 8;10(7):1724. doi: 10.3390/cells10071724

Figure 2.

Figure 2

Effect of LPS on ACE2, CCL2, IL-6/8 and TNFα mRNA expression in second trimester human placental explants. Second trimester placental explants were treated with LPS (10 µg/mL), or vehicle for 4 and 24 h and mRNA levels of ACE2 (A), CCL2 (B), IL-6 (C), IL-8 (D) and TNFα (E), were quantified by qPCR (n = 5/group). Data are normalized by the geometric mean of TOP1 and TBP (reference genes). Data are expressed as means ± SEM. Statistical differences were tested using a paired t-test. * p < 0.05, versus vehicle.