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. 2021 Jul 8;10(7):1724. doi: 10.3390/cells10071724

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ACE2 localization in the placenta and in maternal intervillous immune cells. Representative images of ACE2 immunostaining in a placenta from an uncomplicated PTB delivery (A) ACE2 staining was localized predominantly in the syncytiotrophoblast layer (STB), fetal blood vessel (pFECs) and fetal hoefbauer cells (MΦ) of the placental villi. (B) ACE2 also localized to extravillous trophoblast (EVT) within the basal plate of the placenta and in (C) decidual stromal cells. (D) ACE2 expression in maternal neutrophils of maternal blood clot adjacent to the decidua, Sections were counter-stained with hematoxylin. n = 6/group.