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. 2021 Jul 17;10(7):1656. doi: 10.3390/foods10071656

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of ECE treatment on (A) PGE₂, (B) cell viability, (C) COX-2, (D) IL-6, (E) MMP-2, and (F) MMP-8 mRNA expressions in LPS-stimulated HGF-1 cells. Cells were incubated for 24 h in the presence of LPS (5 μg/mL) and ECE. Different letters (a–e) show significant difference (p < 0.05). ECE: Ecklonia cava extract; PGE₂: prostaglandin E₂; COX-2: cyclooxygenase-2; IL-6: interleukin-6; MMP-2: matrix metalloproteinases-2; MMP-8: matrix metalloproteinases-8; LPS: lipopolysaccharide; HGF: human gingival fibroblasts.