Table 1.
Top ten upregulated genes in co-cultured pericytes.
| Gene | Gene Description | Log2 FC (Co- Vs. Mono-Culture) |
FDR p-Value |
|---|---|---|---|
| IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1 | 8.5 | 1.59 × 10−16 |
| MX1 | MX dynamin-like GTPase 1 (interferon-induced) | 7.3 | 7.05 × 10−15 |
| IFI44L | Interferon-induced protein 44-like | 6.2 | 1.80 × 10−13 |
| CXCL8 | Chemokine (C-X-C motif) ligand 8 | 5.8 | 3.89 × 10−12 |
| IFI6 | Interferon, alpha-inducible protein 6 | 5.2 | 1.30 × 10−9 |
| XAF1 | XIAP associated factor 1 | 5.2 | 1.58 × 10−13 |
| SAMD9L | Sterile alpha motif domain containing 9-like | 5.2 | 1.61 × 10−9 |
| SAMD9 | Sterile alpha motif domain containing 9 | 5.2 | 2.18 × 10−11 |
| OAS1 | 2-5-oligoadenylate synthetase 1 | 5.1 | 4.12 × 10−14 |
| RCAN1 | Regulator of calcineurin 1 | 4.8 | 4.36 × 10−13 |
Log2 fold changes (log2FC) and adjusted P-values are depicted in the third and fourth column, respectively. Comparison of gene expression data of co-culture vs. mono-culture of PCs in triplicates was performed by using Transcriptome Analysis Console (TAC, Applied Biosystems). For the analysis a fold change (FC) cut-off of 1.5 (≈log2FC +/− 0.59) and FDR p-Value of 0.05 was applied.