Table 4.

Association between the vitamin C protocol and ICU mortality.

	Crude		Propensity-Adjusted		PS-Matched		IPTW-Matched
	Unadjusted HR (95% CI)	p	Adjusted HR (95% CI)	p	Adjusted HR (95% CI)	p	Adjusted HR (95% CI)	p
ICU mortality	0.57 (0.35–0.93)	0.02	0.60 (0.34–1.08)	0.09	0.55 (0.30–0.99)	0.047	0.67 (0.45–1.00)	0.048

The propensity-adjusted multivariable analysis was adjusted for lactate concentration and individual PS. The PS- and IPTW-matched multivariable analysis was adjusted for lactate concentration. CI: confidence interval; HR: hazard ratio; ICU: intensive care unit; IPTW: inverse probability of treatment weighting; PS: propensity score.