Table 2.
Numbers and percentages of features affected by the delineation method (VOIvital-tumour vs. VOIgross-tumour) per feature class for the different cohorts and both cohorts together. Differences in the number of affected features between cohorts were assessed using the Fisher’s exact test. NSCLC: non-small cell lung carcinoma, PPGL: pheochromocytoma and paraganglioma, GLCM: grey level cooccurrence matrix, GLRLM: grey level run length matrix, GLSZM: grey level size zone matrix, GLDM: grey level dependence matrix, NGTDM: neighbouring grey tone difference matrix.
| Feature Class | All (n = 43) | NSCLC (n = 12) | PPGL (n = 31) | p-Value |
|---|---|---|---|---|
| First order (18) | 17 (94%) | 13 (72%) | 16 (89%) | 0.402 |
| Shape (14) | 11 (79%) | 7 (50%) | 7 (50%) | 1.000 |
| Texture (73) | 58 (79%) | 48 (66%) | 60 (82%) | 0.024 |
| GLCM (22) | 15 (68%) | 12 (55%) | 15 (68%) | 0.537 |
| GLRLM (16) | 15 (94%) | 12 (75%) | 15 (94%) | 0.333 |
| GLSZM (16) | 12 (75%) | 11 (69%) | 13 (81%) | 0.685 |
| GLDM (14) | 12 (86%) | 9 (64%) | 13 (93%) | 0.165 |
| NGTDM (5) | 4 (80%) | 4 (80%) | 4 (80%) | 1.000 |
| Total (105) | 86 (82%) | 68 (65%) | 83 (79%) | 0.031 |