Figure 2.

A significantly enriched gene network is constructed from the list of genes found through GWAS approaches using the online tools STRING and Cytoscape, that allowed to identify hubs (genes with the highest degree of connection, ESR1 and FN1). Functional annotation using BINGO led to discover the most enriched molecular functions, connected to GTP metabolism and Protein binding, in a broad sense. The Edge count associated with the color is proportional to the number of links connecting the different genes.