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. 2021 Jun 26;11(7):607. doi: 10.3390/jpm11070607

Figure 2.

Figure 2

An electrophysiological analysis in the mPFC of miPiccolo mice. (A) Ratio of paired-pulse facilitation in the mPFC (n = 5). Representative slope pairs evoked with 60-ms interstimulus intervals are shown for the brain slice acutely prepared from the Mock and miPiccolo mice. * p < 0.05 vs. Mock (Student’s t-test). (B) Left panel: Long-term potentiation (LTP) in the mPFC (n = 5). fEPSP: field excitatory postsynaptic potential, TBS: theta burst stimulation (TBS). Right panel: The potentiation rate was calculated by comparing the average slope 55–60 min after the TBS (n = 5). ** p < 0.01 vs. Mock (Student’s t-test). (C) Left panel: Saturation of LTP in the mPFC (n = 5). Right panel: The potentiation rate was calculated by comparing the average slope 55–60 min after the first TBS (n = 5). ** p < 0.01 vs. Mock (Student’s t-test).