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Hispanic patients with HCC have high numbers of mutations (A) and higher concentrations of cfDNA (B) compared to Hispanic subjects with APRI ≥ 1. Data are presented as mean ± SEM. (C,D) IPA core analysis identified top canonical pathways and top upstream regulators for mutated genes in cfDNA of Hispanic subjects with HCC (C) and mutated genes in cfDNA of Hispanic subjects with APRI ≥ 1 (D). APRI, Aspartate transaminase to Platelet Ratio Index.
