Table 3.
p-values of univariate analysis of PFS and OS according to each sICs.
| sICI Median Value (pg/mL) | PFS | OS |
|---|---|---|
| BTLA > 2035 | 0.700 | 1.000 |
| CD137 > 76 | 0.700 | 0.600 |
| CD27 > 3211 | 0.800 | 0.900 |
| CD28 > 885 | 0.700 | 0.400 |
| CD80 > 1019 | 0.700 | 0.700 |
| CTLA4 > 402 | 0.900 | 0.400 |
| GITR > 13 | 0.700 | 0.900 |
| HVEM > 6 | 0.300 | 0.300 |
| IDO > 56 | 1.000 | 0.700 |
| LAG3 > 377 | 0.047 | 0.001 |
| PD-L1 > 2 | 0.800 | 0.500 |
| PD-L2 > 9257 | 0.600 | 0.300 |
| PD-1 > 98 | 0.700 | 0.900 |
| Tim3 > 4028 | 0.700 | 0.600 |
The cutoff of investigated groups is the median value of sICs expressed in pg/mL. PFS: progression-free survival; OS: overall survival; variables significantly associated to PFS or OS are indicated in bold p ≤ 0.05.