Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Impact of different NPM1 mutations on p53 pathway. (A,B) Western blot showing p14ARF, p21, and p53 protein levels in HL-60 (A) and SHI-1 cells (B) transfected with pEGFP-NPM1wt, pEGFP-NPM1mutB (A-like), and pEGFP-NPM1mut7 (non-A-like) plasmids. GAPDH was used as calibrator. Histograms show protein quantification using ImageJ software, and normalized with respect to GAPDH levels.
