Table 3.

Results of fitting the linear superimposition model (LSM) (i = 1) to experimental data of curcumin release in CMC-based films with free curcumin and CMC-based films with curcumin-loaded nanohydrogels. Evaluation of the quality of the regression on the basis of RMSE and R². Estimates’ precision is evaluated using the standardized halved width (SHW) % in parenthesis.

	RMSE	R 2	MF	KF	MR	KR
CMC-films with free curcumin	0.265	0.925	3.645 (27.85%)	9.579 (32.14%)	8.649 (47.35%)	5.124 (20.18%)
CMC-films with curcumin-loaded nanohydrogels	0.321	0.945	6.077 (57.35%)	14.845 (36.58%)	14.069 (19.87%)	16.941 (27.24%)

RMSE—Root mean square error. M_F—Mass of compound released by Fickian transport. K_F—Fickian diffusion rate constant. M_R—Mass of compound released by relaxation of the matrix. K_R—Relaxation rate constant.