Figure 5.

Decreased morphological complexity of carmustine treated astrocytes in vitro. (A,B). Astrocytes from control and carmustine-treated mice. The morphological complexity and extent of astrocyte processes are evident in this representative image at DIV5. (B). Astrocytes from carmustine treated mice showed a reduced number of processes that were retracted. (C). Comparative analysis between the control group and the carmustine-treated group for each parameter: soma area, soma perimeter, soma diameter, number of processes and length of the processes. (3 to 5 astrocyte cells were analyzed from each experiment; Control n = 4, Carmustine n = 4). Data are represented as the mean ± standard error of the mean. ** indicates significant difference (p < 0.001).