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Synthesis of compound 1. Reagents and conditions: (i) dimethylformamide dimethyl acetal, DMF, 24 h; (ii) cyanothioacetamide, NaH, dimethylformamide, 24 h, 82% (over 2 steps); (iii) 2-bromo-N-(3-chloro-2-methylphenyl)acetamide, sodium carbonate, ethanol, 24 h, 28%.
