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. 2021 Jul 19;26(14):4357. doi: 10.3390/molecules26144357

Figure 2.

Figure 2

Chromatograms of 5,6-PQ, 8-aminoquinoline (8-AQ), and PQ in human plasma and urine. (A) Blank plasma with an internal standard (IS). (B) Spiked plasma at low limit of quantitation (LLOQ) for PQ and 5,6-PQ. (C) Spiked plasma at 600 ng/mL for PQ and 5,6-PQ. (D) Spiked plasma at 1500 ng/mL for PQ and 5,6-PQ. (E) A clinical trial plasma sample. (F) Blank urine with an IS. (G) Spiked urine at LLOQ for PQ and 5,6-PQ. (H) Spiked urine at 600 ng/mL for PQ and 5,6-PQ. (I) Spiked urine at 1500 ng/mL for PQ and 5,6-PQ. (J) A clinical trial urine sample.