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Tumor-associated macrophages polarization model in hematologic malignancies. TAM, tumor-associated macrophages; GM-CSF, granulocyte and monocyte colony stimulating factor; IFN, interferon; TNF, tumor necrosis factor; LPS, lipopolysaccharide; M-CSF, monocyte colony stimulating factor; IL, interleukin; TNF, tumor necrosis factor; NO, nitric oxide; ROS, reactive oxygen species; CXCL, chemokine ligands with C-X3-C motif; Th, T helper; TGF, tumor growth factor.
