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ZEB2 Gene and protein architecture: (A) human ZEB2 gene exon/intron is represented. Exon 8 encodes for about 60% of the protein. (B) ZEB2 protein structure. NIM: NuRD-Interacting Motif, NZF; CZF: N- and C-terminal Zinc Finger clusters; SBD: Smad-Binding Domain. The star in the SBD represents the essential residues in the SBD [91]; HD: Homeodomain-like Domain, CID: CtBP-Interacting Domain.
