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. 2021 Jul 8;22(14):7347. doi: 10.3390/ijms22147347

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Solubility profiles of theophylline at 25 °C in mixtures comprising NADES successfully diluted with water. On the ordinate, $x_{NADES}^{*}$ , represents values of the mole fractions of Natural Deep Eutectic Solvent in aqueous solutions. For comparison purposes, solubility in DMSO+water was plotted as a function of $x_{2}^{*}$ (grey line).