Table 1.
Clinical characteristics of study patients.
| Characteristics | Total (n = 377) | Aged < 3 Years (n = 171) | Aged 3–14 Years (n = 206) | p-Value |
|---|---|---|---|---|
| Sex (%) | 0.0019 | |||
| Male | 197 (52.3) | 74 (43.3) | 123 (59.7) | |
| Female | 180 (47.7) | 97 (56.7) | 83 (40.3) | |
| Age, median, years (range) | 3.5 (0.4–14.9) | 1.5 (0.4–2.9) | 5.5 (3.0–14.9) | NA |
| Clinical manifestations (%) | ||||
| Fever | 363 (96.3) | 169 (98.8) | 194 (94.2) | 0.0254 |
| Cervical lymphadenopathy | 29 (7.7) | 4 (2.3) | 25 (12.1) | 0.0003 |
| Tonsillar swelling or exudates | 363 (96.3) | 170 (99.4) | 193 (93.7) | 0.0043 |
| Cough | 156 (41.4) | 73 (42.7) | 83 (40.3) | 0.6749 |
| Rhinorrhea | 174 (46.2) | 88 (51.5) | 86 (40.3) | 0.0627 |
| Conjunctival injection | 17 (4.5) | 7 (4.1) | 10 (4.9) | 0.8065 |
| Oral ulcers or vesicles | 20 (5.3) | 13 (7.6) | 7 (3.4) | 0.1042 |
| Diarrhea | 61 (16.2) | 36 (21.1) | 25 (12.1) | 0.0242 |
| Hoarseness | 9 (2.4) | 6 (3.5) | 3 (1.5) | 0.3100 |
| No. of viral features (%) | 0.0060 | |||
| 0 | 118 (31.3) | 43 (25.1) | 75 (36.4) | |
| 1–2 | 230 (61.0) | 110 (64.3) | 120 (58.3) | |
| ≥3 | 29 (7.7) | 18 (10.5) | 11 (5.3) | |
| Seasonal distribution (%) | 0.2144 | |||
| March–May | 74 (19.6) | 34 (19.9) | 40 (19.4) | |
| June–August | 155 (41.1) | 62 (36.3) | 93 (45.1) | |
| September–November | 99 (26.3) | 49 (28.7) | 50 (24.3) | |
| December–February | 49 (13.0) | 26 (15.2) | 23 (11.2) | |
| No. of patients tested for RV PCR (%) | 192 (50.9) | 102 (59.6) | 90 (43.7) | 0.0026 |
| Positive rate of RV PCR, % | 34.9 | 33.3 | 36.7 | 0.6515 |
| No. of patients tested for EV PCR (%) | 130 (34.5) | 63 (36.8) | 67 (32.5) | 0.3259 |
| Positive rate of EV PCR, % | 41.5 | 41.3 | 41.8 | 1.0000 |
NA, nonapplicable; RV, respiratory viruses; PCR, polymerase chain reaction; EV, enterovirus.