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. 2021 Jul 6;12(7):1043. doi: 10.3390/genes12071043

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Pedigree of the Italian family. Pedigree of the four-generation family investigated in the present study. Filled symbols represent affected individuals. The age of each individual and the co-segregation of the NCOA3 variant with HL (NM_181659.3, c.2909G>C, p.(Gly970Ala)) are reported. Their ages are indicated followed by the terms y.o., meaning years old. The labels used to report the subjects’ genotypes are G/G for homozygous wild type and G/C for the individuals carrying the variant herein discussed in heterozygosis. Individuals with Roman numeric labels were analyzed in this study.