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. 2021 Jul 12;22(14):7444. doi: 10.3390/ijms22147444

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Montelukast exhibited a suppressive effect on pancreatic carcinogenesis in the hamster pancreatic cancer model. (A) Experimental design for the BOP-induced pancreatic cancer model in hamster. Anti-allergic drugs: montelukast, bambuterol and levocetirizine. (B) Representative images of pancreatic cancer in the hamster model (the cancer lesion is indicated by the yellow arrow) and H&E staining of the cancer lesion. Bar = 100 µm. (C) Cancer incidence and (D) multiplicity in the four groups.