Figure 4.

Normalized sensitivity distribution (S_normal), including the planar sensitivity distribution along the cell barrier surface (rainbow colour map) in the x–y plane and sensitivity distribution along the cell barrier though the axis (lines AA’) shown in the scheme of the model at the left, when TEER was measured for (a) BoC device with concentric electrodes occupying 15% total area (BoC A) and occupying 65% total area (BoC B) and when TEER was measured (b) using chopstick electrodes in an insert culture insert with 12 mm diameter (Insert A) and 6.5 mm diameter (Insert B). Results are presented for different TEERS (10¹–10³ Ω·cm²). An S_normal value of 0% represents the zone of lower sensitivity. Note that axes have different scales.