Table 3.
The mechanism of circRNAs as ceRNAs in GC.
| CircRNA | The Mechanism of ceRNA | Biological Functions | Reference |
|---|---|---|---|
| circNRIP1 | miR-149-5p/AKT1/mTOR | Proliferation, migration, invasion | [172] |
| circRNA has_circ_0001368 | miR-6506-5p/FOXO3 | Proliferation | [173] |
| circCOL6A3 | miR-3064-5p/COL6A3 | Proliferation, migration, apoptosis | [174] |
| circRNA0047905 | miR-4516/miR-1227-5p/SERPINB5/MMP11 | Proliferation | [175] |
| circCACTIN | miRNA-331-3p/TGFBR1 | Proliferation | [176] |
| circGRAMD1B | miR-130a-3p/PTEN/p21 | Proliferation, migration, invasion | [177] |
| circ-ZNF609 | miRNA-145-5p | Proliferation, migration | [178] |
| circRHOBTB3 | miR-654-3p/p21 | Proliferation | [179] |
| circ_0006282 | miR-155/FBXO22 | Proliferation, migration | [180] |
| circCCDC9 | miR-6792-3p/CAV1 | Proliferation | [181] |
| circ-MAT2B | miR-515-5p/HIF-1α | Proliferation | [182] |
| circCYFIP2 | miR-1205/E2F1 | Proliferation, invasion | [183] |
| circ_0081143 | miR-497-5p/EGFR | migration, invasion, EMT | [184] |
| CircHIPK3 | miR-876-5p/PIK3R1 | Proliferation, migration, invasion | [185] |
| circRNA_100782 | miR-574-3p/Rb | Proliferation, invasion | [186] |
| hsa_circ_0005556 | miR-4270/MMP19 | Proliferation, migration, invasion | [187] |
| circPDZD8 | miR-197-5p/CHD9 | Proliferation, migration | [188] |
| circ-ITCH | miR-199a-5p/Klotho | Migration | [189] |