Table 2.
Experiments which evaluated the feasibility of human ovarian xenotransplantation into animals.
| Evaluation | Animal | Materials | Transplantation Site | Publication |
|---|---|---|---|---|
| Oocyte maturation after xenotransplantation | SCID mice | Ovarian tissue | Back muscle, kidney capsule | Soleimani et al. [212] |
| SCID mice | Ovarian tissue | Kidney capsule | Gook et al. [213,214] | |
| SCID mice | Ovarian tissue | Neck muscle | Lotz et al. [215] | |
| SCID mice | Ovarian tissue | Subcutaneous space | Kim et al. [216] | |
| Follicular development | SCID mice | Ovarian tissue | Intraperitoneum | Ayuandari et al. [217] |
| NOG mice | Ovarian cortex | Back skin, kidney capsule, ovarian bursa | Terada et al. [218] | |
| SCID mice | Clot containing preantral follicle | Ovarian bursa | Dolmans et al. [219] | |
| SCID/hpg mice | Ovarian tissue | Kidney capsule | Oktay et al. [220] | |
| Swiss nu/nu mice | Ovarian tissue | Intraperitoneum | David et al. [221] | |
| NOD/SCID mice | Ovarian tissue | Subcutaneous space | Weissman et al. [222] | |
| NMRI nu/nu | Ovarian tissue | Intraperitoneum, subcutaneous space, ovarian bursa, thigh muscle | Dath et al. [223] | |
| Swiss nu/nu mice | Clot containing preantral follicle | Intraperitoneum | Paulini et al. [224] | |
| SCID mice | Ovarian tissue | Intraperitoneum | Amorim et al. [225] | |
| NMRI nu/nu | Ovarian tissue | Thigh muscle | Jafarabadi et al. [226] | |
| NOD/SCID mice | Ovarian cortex | Subcutaneous space | Campos-Junior et al. [227] | |
| Optimization of grafting protocols | NMRI nu/nu | Ovarian tissue | Intraperitoneum | Van Eyck et al. [228] |
| SCID mice | Ovarian cortex | Back muscle | Soleimani et al. [69] | |
| B6cg nude mice | Ovarian tissue | Back skin, thigh muscle | Hormozi et al. [229] | |
| NOD/SCID mice | Ovarian cortex | Kidney capsule, subcutaneous space | Hernandez-Fonseca et al. [230] | |
| SCID mice | Ovarian tissue | Neck muscle | Maltaris et al. [231] | |
| Balb/C nu/nu | Ovarian tissue | Back muscle | Friedman et al. [232] | |
| SCID mice | Ovarian stroma | Subcutaneous space | Fu et al. [233] | |
| NMRI nu/nu | Ovarian tissue | Intraperitoneum | Van Langendonckt et al. [234] | |
| New Zealand rabbits | Ovarian tissue | Back muscle | Wang et al. [235] | |
| Balb/C nu/nu | Ovarian tissue | Ovarian bursa, subcutaneous space | Ruan et al. [236] | |
| Reimplantation of malignant cells | SCID mice | Ovarian cortex | Intraperitoneum | Luyckx et al. [237] |
| NOD/SCID mice | Ovarian tissue | Subcutaneous space | Kim et al. [238] | |
| NMRI nu/nu | Ovarian tissue | Subcutaneous space | Greve et al. [239] | |
| SCID mice | Ovarian tissue | Neck muscle | Lotz et al. [240] | |
| SCID mice | Ovarian tissue | Intraperitoneum | Dolmans et al. [241] |
NMRI: National Medical Research Institute; NOD: non-obese diabetic/severe combined immunodeficient; NOG: non-obese diabetic/severe combined immunodeficient/γcnull; SCID: severe combined immunodeficient; SCID/hpg: severe combined immunodeficient/hypogonadism.