Table 2.

Cox proportional hazards modelling of factors known to be associated with survival and individual chitinase proteins separately. b—regression coefficient; SE—standard error, Wald statistic; HR—hazard ratio; CI—confidence interval.

Covariate	b	SE	Wald	p	HR	95% CI of HR
Age at onset	0.076	0.033	5.206	0.023	1.079	1.011 to 1.153
Disease duration at sampling	−0.099	0.043	5.428	0.020	0.906	0.833 to 0.984
CHIT1	−0.777	0.541	2.060	0.151	0.460	0.159 to 1.328
Age at onset	0.049	0.032	2.291	0.130	1.050	0.986 to 1.119
Disease duration at sampling	−0.096	0.042	5.301	0.021	0.908	0.837 to 0.986
CHI3L1	−0.398	0.531	0.562	0.453	0.672	0.237 to 1.902
Age at onset	0.115	0.055	4.454	0.035	1.122	1.008 to 1.249
Disease duration at sampling	−0.116	0.045	6.666	0.010	0.890	0.815 to 0.972
CHI3L2	−1.604	0.685	5.478	0.019	0.201	0.053 to 0.771
Age at onset	0.065	0.032	4.078	0.043	1.068	1.002 to 1.137
Disease duration at sampling	−0.059	0.033	3.264	0.071	0.942	0.884 to 1.005
pNFH	−0.890	0.537	2.741	0.098	0.411	0.143 to 1.178