Figure 1.

Time lapse of cells recruited into a wound. During the first phase, platelets and neutrophils are recruited, and then monocytes are recruited and infiltrate the tissue and differentiate into macrophages; resident macrophages can also proliferate. Altogether, this leads lead to fibrocyte recruitment and fibroblast proliferation and the posterior conversion to myofibroblasts. Other cells such as lymphocytes—mainly T cells—are also recruited in low numbers at the late stages. This figure does not show the NK, dendritic cells and mast cells; usually their numbers are extremely low, but still they can play an important role on the process.