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. 2021 Jul 15;26(14):4301. doi: 10.3390/molecules26144301

Figure 6.

Figure 6

(A) In vivo assays with C. elegans (CL2006 and N2). (a) Fluorescence images of CL2006 (a1,a2) and N2 (a3,a4) nematodes that were co-stained with ThT and CPDs. (b) Fluorescent images of inhibiting Aβ deposits after treating without (b1,b2) or with (b3,b4) CPDs in CL2006 nematodes. Reprinted with permission from reference [101]. Copyright 2020 Wiley-VCH. (B) Schematic of bPEI@CDs’ capabilities regarding inhibiting Aβ assembly and disaggregating preformed fibrillar aggregates. Reprinted with permission from reference [102]. Copyright 2017 Wiley-VCH. (C) Schematic of Aβ-targeting, CD-mediated photomodulation modality for the spatiotemporal inhibition of Aβ aggregation in vivo. Reprinted with permission from reference [103]. Copyright 2020 American Chemical Society.