Figure 3.

SARS-CoV-2 promotes the release of cytokines and angiogenic molecules from HL-mECs. HL-mECs were treated with infectious (SARS-CoV-2) or UV inactivated (UV-SARS-CoV-2) SARS-CoV-2 at MOI 1, for 1 h at 37 °C and then washed and cultured until day 3 p.i. Supernatants of SARS-CoV-2 and UV-SARS-CoV-2 HL-mECs were evaluated at 1 (left panel), 2 (middle panel), and 3 (right panel) days p.i. for the presence of (A) cytokines or (B) angiogenic molecules by human proteome arrays. The results are expressed as mean values ± SD of duplicates given as fold increase as compared to mock-infected cells. Data are representative of one out of three independent experiments with similar results.